Therapy for HDV!
نویسندگان
چکیده
منابع مشابه
HDV+HBV hepatitis reactivation due to immunossuppressive therapy for hematological malignancies – an increasingly complex challenge
Background Hepatitis B virus reactivation (HBV-R) is becoming an increasingly concerning issue as monoclonal antibody therapy has become widely used for chronic lymphoproliferations. HBV-R can also occur in HBsAg negative patients who have only HBcAb positive (occult HBV infection). We present a non-consecutive HBV-R case series report. Our series consisted of both HBsAg positive patients and p...
متن کاملChances for cure in chronic HBV/HDV coinfection
Background Worldwide, chronic infection with HBV and HDV occurs in more than 10 million people with higher rates of developing cirrhosis, hepatic decompensation and hepatocellular carcinoma. Peginterferon (pegIFN) for 48 weeks is one of the current therapies, with poor response rates; prolonging therapy beyond 12 months might be of benefit for the patients. In order to assess the response to a ...
متن کاملLate HDV RNA relapse after peginterferon alpha-based therapy of chronic hepatitis delta.
UNLABELLED Interferon alpha is the only treatment option for hepatitis delta virus (HDV). Trials investigating the efficacy of pegylated interferon alpha (PEG-IFNa) showed HDV RNA negativity rates of 25-30% 24 weeks after therapy. However, the clinical and virological long-term outcome of HDV-infected patients treated with PEG-IFNa is unknown. We performed a retrospective-prospective follow-up ...
متن کاملPacific Islands High HDV Prevalence Intermediate Low
Received January 8, 2015; accepted May 7, 2015. From the Baylor College of Medicine, Houston, TX, the yDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, and the zGastroenterology, Hepatology and Nutrition, Texas Children’s Liver Center, Houston, TX. Address correspondence and reprint requests to Daniel H. Leung, MD, Baylor College of Medicine, Ga...
متن کاملInitiation of hepatitis delta virus (HDV) replication: HDV RNA encoding the large delta antigen cannot replicate.
The hepatitis delta virus (HDV) nucleocapsid consists of a genomic-length RNA of 1.7 kb and approximately equimolar amounts of the small and large forms of the hepatitis delta antigen (S-HDAg and L-HDAg, respectively). Since HDV RNA particles contain not only a genomic RNA species encoding S-HDAg but also an RNA species encoding L-HDAg, which is produced by an RNA-editing process, the question ...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2003
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.510380631